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Thymulin 10mg 3mL Lyophilized Powder
£595.00
£505.00
MOA
- Immune Modulation:
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- T-Cell Differentiation and Activation:
- Thymulin is essential for the maturation and differentiation of T-lymphocytes in the thymus.
- It enhances the activity of cytotoxic T cells (CD8+) and helper T cells (CD4+), boosting immune surveillance and response.
- T-Cell Differentiation and Activation:
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- Enhancement of Natural Killer (NK) Cell Activity:
- Increases the cytotoxic activity of NK cells, improving innate immune defense against infections and tumors.
- Regulation of Cytokine Production:
- Thymulin modulates the production of key cytokines such as interleukin-2 (IL-2) and interferon-gamma (IFN-γ), both critical for robust immune responses.
- Enhancement of Natural Killer (NK) Cell Activity:
- Neuroendocrine-Immune Axis:
- Interaction with Hormonal Systems:
- Thymulin operates at the intersection of the immune and endocrine systems.
- Its activity is influenced by zinc ions (Zn²⁺), which are necessary for its biological activity. Thymulin binds zinc to form an active complex that interacts with immune cell receptors.
- Feedback with Hypothalamic-Pituitary-Adrenal (HPA) Axis:
- Thymulin influences the HPA axis by modulating the release of hormones such as cortisol, which can suppress excessive immune responses and inflammation.
- Interaction with Hormonal Systems:
- Anti-Inflammatory Effects:
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- Regulation of Inflammatory Mediators:
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- Thymulin downregulates pro-inflammatory cytokines, reducing excessive inflammation in conditions like autoimmune diseases or chronic inflammation.
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- T Regulatory (Treg) Cell Promotion:
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- Enhances the activity of Treg cells, which help maintain immune tolerance and prevent autoimmune reactions.
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- Cellular Receptor Activation:
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- Binding to Thymulin Receptors:
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- Thymulin interacts with specific receptors on T-cells, monocytes, and other immune cells, triggering intracellular signaling cascades that modulate their activity.
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- Signal Transduction Pathways:
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- Activates pathways like JAK/STAT and MAPK, which are involved in cell survival, proliferation, and cytokine production.
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More Information
- Disclaimer: For Research Purposes Only – All products on this site are for Research and Development use only. The statements made within this website have not been evaluated by the US Food and Drug Administration. The statements and the products of this company are not intended to diagnose, treat, cure or prevent any disease. Celia Health is a supplier of research-use chemicals manufactured in a CGMP facility in the US. Celia Health is not a compounding pharmacy or chemical compounding facility as defined under 503A of the Federal Food, Drug, and Cosmetic act.
